Real Madrid boss Zinedine Zidane has injury concerns ahead of Wednesday night’s Champions League clash with Tottenham Hotspur.
Zidane could find himself without Isco, Raphael Varane, Gareth Bale and number one keeper Keylor Navas for the trip to Wembley stadium.
Reports had surfaced that Bale would recover in time to face his former club, but he trained alone on Monday at Valdebebas and is now a major doubt.
Navas, who has missed Madrid’s last three games with an abductor problem – is also likely to miss out and be replaced by Kiko Casilla.
Both Isco and Varane suffered knocks in the 2-1 defeat to Girona on Sunday evening and they trained alone and indoors on Monday morning.
Dani Carvajal and Mateo Kovacic remain still sidelined, meaning Zidane has a selection headache before meeting Mauricio Pochettino’s side.
Madrid and Spurs are level on seven points each in Champions League Group H and a victory for either will guarantee them a place in the knockout stages of the competition.
Having started the season in stuttering form, Madrid had bounced back slightly with wins over Eibar, Getafe, Espanyol and Alaves.
However, their run of successive victories came to an end on Sunday after a shock defeat to Catalan side Girona.
Isco’s opening goal was cancelled out by Cristhian Stuani, before Portu grabbed a winner for the newly promoted La Liga side.