Barcelona could qualify for the last-32 of the Champions League with a victory over Olympiacos in Greece on Tuesday evening.
Ernesto Valverde’s side have won all of their games in the competition so far and could qualify with two games spare.
The two sides met two weeks previous in a game which ended 3-1 to the Catalan side but saw their defensive resolve beaten for the first time in the competition.
Gerard Pique, who was dismissed in that game will not travel to Athens and is likely to be replaced by Javier Mascherano, although talk of a start for Thomas Vermaelen has surfaced.
Andres Iniesta is also a doubt after missing the weekend win over Athletic Club with a knock, and Gerard Deulofeu will be hoping to return to the starting eleven.
Lionel Messi will lead the line for the visitors, alongside Luis Suarez and one other – likely to be Deulofeu or Paco Alcacer, who scored in the Copa del Rey last week.
The hosts, meanwhile, will be without Seba and El Fardou Ben Nabouhane, but Emmanuel Emenike and former Barca man Botia are available.
Olympiacos possible starting lineup:
Proto; Elabdellaoui, Engels, Botia, Koutris; Romao, Odjidja-Ofoe, Pardo, Fortounis, Androutsos; Emenike
Barcelona possible starting lineup:
Ter Stegen; Roberto, Mascherano, Umtiti, Digne; Paulinho, Busquets, Iniesta; Deulofeu, Suarez, Messi