Barcelona breezed to a 2-0 win over Sporting Lisbon thanks to goals from Paco Alcacer and a Jeremy Mathieu own goal.
With the Catalan giants already qualified for the last-16 of the Champions League; Valverde opted to make several changes which included a rest for both Sergio Busquets and Lionel Messi.
The likes of Aleix Vidal, Denis Suarez and Paco Alcacer were handed a chance to impress and it was the latter who did just that to open the scoring.
Croatian midfielder Ivan Rakitic has featured in every single Barcelona match this season and it was his corner which found Alcacer, who headed past Rui Patricio in the visitors goal.
Bas Dost had chances in the second half but reserve keeper Jasper Cillessen was not to be beaten on a largely easy night for the home side.
The introduction of Messi with half an hour to play saw Barca shift through the gears and it was his pass to Denis Suarez, who crossed in only for former player Mathieu to slide the ball into his own net.
Barca finish the group as winners and will now wait to see who their opponent is in the next round.
Elsewhere, Atletico Madrid were handed an early exit after being held by Chelsea at Stamford Bridge.